| 8:30 AM - 9:15 AM | Check-In, Breakfast, and Welcome Remarks 8:30 AM
Check-In and Breakfast
9:00 AM
Welcome Remarks
Megan Prescott, PhD, The New York Academy of Sciences |
| 9:15 AM - 10:00 AM | Keynote Presentation Keynote Presentation: Decoding Proteinopathies: From Misfolded Proteins to Neurodegenerative disease mechanisms
Virginia Lee, PhD, University of Pennsylvania |
| 10:00 AM - 10:35 AM | Networking Break |
| 10:35 AM - 12:05 PM | Session I: Disease Mechanisms Associated With Protein Aggregation and Novel Strategies to Target and Treat Proteinopathies 10:35 AM
Targeting ESCRT-III Proteins to Mitigate TDP-43 Proteinopathy in ALS/FTD
Alyssa Coyne, PhD, Johns Hopkins University School of Medicine
11:05 AM
Countering Deleterious Phase Transitions in Neurodegenerative Disease
James Shorter, PhD, University of Pennsylvania
11:35 AM
TDP-43 Gene Therapy
Sarah Tisdale, Regeneron |
| 12:05 PM - 12:35 PM | Session II: Short Talks from Submitted Abstracts 12:05 PM
Short Talk 1
Speaker, Affiliation
12:15 PM
Short Talk 2
Speaker, Affiliation
12:25 PM
Short Talk 3
Speaker, Affiliation |
| 12:35 PM - 1:55 PM | Networking Lunch and Poster Session |
| 1:55 PM - 3:25 PM | Session III: Targeting Lysosomal and Lipid Dysfunction as a Unified Approach for Treating Proteinopathies 1:55 PM
Genetic Links between TMEM106b, Lysosome Function, and Neurodegenerative Disease
Roberto Zoncu, PhD, Northwestern University
2:25 PM
The Phase of Fat: Mechanisms of Lipid Storage
Tobias C. Walther, PhD, Memorial Sloan Kettering Cancer Center; HHMI
2:55 PM
To Be Announced |
| 3:25 PM - 4:00 PM | Networking Break |
| 4:00 PM - 5:30 PM | Session IV: Modulating Innate and Adaptive Immune Function to Modify Neurodegeneration 4:00 PM
To Be Announced
4:30 PM
Peripheral-to-Central Immune Infiltration and Reprogramming in ALS
Evangelos Kiskinis, PhD, Northwestern University
5:00 PM
To Be Announced
5:30 PM
Symposium Adjourns |