Agenda

Melanie Brickman Borchard, PhD, MSc, The New York Academy of Sciences
Yael David, PhD, Memorial Sloan Kettering Cancer Center
Tania Lupoli, PhD, New York University  

12:45 PM

Keynote Presentation: Engineering Translation for Chemistry, Biology, and Medicine
Alanna Schepartz, PhD, University of California, Berkeley

1:25 PM

Mapping Sub-Condensate Chemical Landscapes via Fluorescence Lifetime Imaging
Moeka Sasazawa, New York University 

1:35 PM

A Structure-Guided Strategy Reveals a Cryptic Allosteric Switch in BCL-XL
Oi Wei Mak, PhD, Albert Einstein College of Medicine 

1:45 PM
Discovery of a New RNA Modification Triggering Cellular Translational Stress via Chemical Biology Approaches 
Anna Knoerlein, PhD, Memorial Sloan Kettering Cancer Center   

2:30 PM

Substrate-Derived Peptides for Selective Covalent Inhibition of Protein Tyrosine Kinases
Minhee Lee, Columbia University 

2:32 PM

Development of Crosslinked Helix Dimer Protein Degraders
Joseph Ongkingco, New York University 

2:34 PM

Towards the AI-Guided Development of Novel Living-Yeast Biosensors: a Platform for the Prediction, High-throughput Synthesis, and Screening of Novel G-Protein Coupled Receptors 
Adriana Di Nanni, PhD, Columbia University 

2:36 PM

Autophagy–Lysosome Targeting Heterobifunctional Chimeras as Therapeutic Approaches 
Xiaoqing Han, PhD, Merck 

2:38 PM

Inhibiting the Folding Activity of Human Hsp70s with Selective Peptidomimetics 
Gideon Yawson, New York University 

2:40 PM

Development of Minimalistic Radical-Trapping Probes for Labeling Protein Thiyl Radicals 
Ruocheng Yu, PhD, Harvard University 

2:50 PM

Kinetic Selectivity of Kinase Inhibitors 
Madeeha Ali, PhD, Stony Brook University 

3:00 PM

Elucidation of the Mechanism-of-Action of Empirically-Isolated, Breakthrough Folding-Corrector Drugs via Cryo-EM Reconstruction of Protein Folding Intermediates 
Andrew Paige, Columbia University 

Thomas A. Paul, PhD, Pfizer