Sarah Slavoff, PhD
Yale University
Sarah Slavoff, PhD, is an Associate Professor in the Departments of Chemistry and Molecular Biophysics and Biochemistry at Yale University. She received her Ph.D. in Biological Chemistry at the Massachusetts of Institute of Technology working with Alice Ting where she developed technologies for chemoenzymatic and biorthogonal protein labeling. During her NIH postdoctoral fellowship Alan Saghatelian at Harvard University, Prof. Slavoff developed the first high-sensitivity liquid chromatography-mass spectrometry proteomic technology for detection of previously undiscovered, short human genes encoding microproteins. Since starting her independent research group at Yale in 2014, Prof. Slavoff has continued to innovate new quantitative and chemoproteomic approaches for functional microprotein discovery, as well as cellular and molecular characterization of microproteins. Her group demonstrated that a dark protein, alt-RPL36, regulates the PI3K signaling pathway, and that phosphorylation of the NBDY microprotein regulates formation of membraneless organelles in human cells. Prof. Slavoff was named a Searle Scholar in 2016 and received a 2022 Mark Foundation for Cancer Research Emerging Leader Award and a 2022 Paul G. Allen Frontiers Group Distinguished Investigator Award.
