Michael Bamkole, MS, is a PhD student at Mayo Clinic Graduate School of Biomedical Sciences in Jacksonville, Florida. His research focuses on cerebrovascular contributions to Alzheimer’s disease, with an emphasis on how APOE genotype influences brain endothelial metabolism and mitochondrial function. His current work uses human iPSC-derived vascular endothelial cells to investigate APOE-dependent alterations in mitochondrial bioenergetics, lipid metabolism, and blood-brain barrier function.