Dr. Jaffee is an internationally recognized expert in cancer immunology and pancreatic cancer.  She studies the pancreatic tumor microenvironment using preclinical models, and tests novel immunotherapies in patients. She is Deputy Director of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Co-Director of the Skip Viragh Pancreatic Cancer and Associate Director of the Bloomberg Kimmel Institute for Cancer Immunotherapy. Dr. Jaffee is known for developing the most successful translational pancreatic cancer program in the country that has served as a model for other outstanding programs.   Dr. Jaffee is a Past President of AACR. She has served on a number of committees at the National Cancer Institute, including the co-chair of the Biden Moonshot Blue Ribbon Panel which identified high impact research priorities for the NCI. She currently serves as Chief Medical Advisor to the Lustgarten Foundation for Pancreatic Cancer Research. She is the inaugural director of the Convergence Institute for Integrating Technologies and Computational Sciences at Johns Hopkins. Dr. Jaffee is a member of the National Academy of Medicine, a Fellow of the American College of Physicians, a Fellow of American Association for the Advancement of Science, a Fellow of the SITC Academy of Immuno-Oncology and a Fellow of the AACR Academy.