Alexander Charney, MD, PhD
Icahn School of Medicine at Mount Sinai
Dr. Alexander Charney is a physician-scientist and academic leader at the Icahn School of Medicine at Mount Sinai, where he holds professorships in Artificial Intelligence, Psychiatry, Genetics, and Genomic Sciences. As Vice Chair of the Windreich Department of AI and Human Health, Director of The Charles Bronfman Institute for Personalized Medicine, Deputy Director of the Hasso Plattner Institute for Digital Health, and Executive Director of the Blau Center for Mental Health, Dr. Charney plays a central role in shaping the future of medicine at Mount Sinai and beyond. Dr. Charney's work bridges psychiatry, neuroscience, genomics, and artificial intelligence. He is renowned for developing large-scale, high-impact research programs—including the Mount Sinai Million Health Discoveries Program and the Living Brain Project—that are redefining how complex diseases are studied and treated. He has served as principal investigator on multiple major NIH grants and leads research efforts into schizophrenia genetics, long COVID, and the integration of AI in medical science. His leadership in the Psychiatric Genomics Consortium has resulted in major advances in understanding the genetic underpinnings of mental illness. As an educator and mentor, Dr. Charney has trained numerous students, fellows, and junior faculty, many of whom now hold leadership positions in academia and research. He also played a formative role in redesigning Mount Sinai's research-track psychiatry residency program, laying the foundation for a new generation of physician-scientists. In his administrative leadership roles, Dr. Charney has driven transformative change—securing major philanthropic and federal funding, launching first-in-human clinical trials (including gene therapy for schizophrenia), expanding institutional partnerships, and recruiting top-tier faculty. His ability to translate scientific discovery into clinical and societal impact has established him as a leader in precision medicine, digital health, and translational neuroscience.
