Dr. Christine Chio is an Assistant Professor of Genetics and Development at Columbia University Irving Medical Center. Her research focuses on the roles of reactive oxygen species and redox metabolism in cancer. She first elucidated how reversible cysteine oxidation regulates transcript-specific translation to support pancreatic tumorigenesis. Using novel chemoproteomic approaches, her group then discovered that proteinaceous methionine oxidation is highly site-specific and that its patterns shift with cellular state, revealing physiological redox switches that influence tumor development. Building on this framework, her team recently identified modular patterns of oxidative modifications that regulate adipose biology across distinct metabolic contexts—such as cancer, thermogenesis, obesity, and aging—uncovering a broader redox code that integrates cellular stress responses with adipose function and whole-body metabolic regulation. Her work has been recognized with awards including the V-Foundation Scholar Award, the Pershing Square Sohn Prize, the Paul Marks Scholar Award, the Ruth Leff Siegel Award, and the Irma Hirschl Scholar Award.